The American Old West has captured the heart of Gregory Mayse since he was a young boy growing up in the small village of Castalia, Ohio. He has now earned a reputation as an award-winning oil painter who features the lives of characters in the Old West.

His earliest oil paintings were done in high school. In college he majored in graphic design, illustration and photography. Following a professional photography career, Gregory returned to his first creative passion of oil painting in 2011.

Gregory has painted hundreds of western scenes and portraits that feature cowboys, cowgirls, Native Americans, pioneers, mountain men, horses and buffalo.

In 2024 he displayed his work and did several painting demonstrations at the National Pony Express Museum in St. Joseph, MO.

In 2025 Gregory donated a painting of Toby Keith to the CFD Museum when Toby was posthumously inducted into the CFD Hall of Fame. It is now part of the permanent collection.